Description of the patient case:
The patient is a 26-year-old Male, who presented to our ER for worsening right elbow bursitis. The patient was seen in the ER 2 days prior for the same issue, underwent a drainage procedure with documented removal of only 1cc, and was started on PO Keflex. Fluid was also sent for culture. Since the last time in the ER, the patient reported worsening pain and spreading redness around the elbow. The patient also reported some intermittent numbness and tingling in the fingers of the right hand. The patient decided to come back in due to concerns about a possible worsening infection. The patient denied any fevers/chills or other systemic symptoms. The patient denied tobacco or alcohol use.
Factors that might have influenced the pharmacokinetic and pharmacodynamic processes of the patient
The patient was not responding to the trial of oral antibiotics. Keflex 500mg PO QID instructed to take one tablet by mouth four times a day for 5 days. Once inpatient, the patient was started on IV vancomycin. Following the initial dose of Vancomycin 1.5gm IV loading dose, he had a mild vancomycin infusion reaction with a pruritic rash on the abdomen that resolved with PO Benadryl dose. Following doses of vancomycin were tolerated better with Benadryl pre-treatment and slowing infusion rate.
One factor to consider in this case was the rate of the IV infusion. “Red Man Syndrome” is used to describe the adverse effect of vancomycin infusion. This anaphylactoid reaction is caused by vancomycin degranulation of mast cells and basophils resulting in histamine release independent of IgE (Rivera & Ryan, 2022). Another factor that may be worth noting is gender. According to Alvarez-Arango et al. (2021), White patients were found more likely to experience Red Man Syndrome than non-White patients. Red Man Syndrome was also identified as more likely to affect male rather than female patients (Alvarez-Arango et al., 2021).
A personalized plan of care
According to Rosenthal & Burchum (2021), one patient may experience adverse effects from a medication, while others may not. Asking the patient to report symptoms during and after the initiation of medication can help with identifying adverse reactions and implementing a plan to treat symptoms. In assessing the risk-to-benefit ratio of medication, one must consider the severity of the side effects (Rosenthal & Burchum, 2021). In this case, vancomycin 1gm IV q12hrs (15mg/kg dosing) was continued. The infusion rate was extended to 120 minutes. The patient was also pretreated with Benadryl 50mg by mouth to prevent infusion reaction.
References:
Alvarez-Arango, S., Michelle, O. S., Sequist, T. D., & Burk, C. M. (2021). Vancomycin infusion reaction — moving beyond “Red man syndrome”. The New England Journal of Medicine, 384(14), 1283-1286. doi:https://doi.org/10.1056/NEJMp2031891
Rivera, C. G., & Ryan, K. L. (2022). Call to Pharmacists: End Use of “Red Man Syndrome.” Annals of Pharmacotherapy, 56(1), 102–103. https://doi.org/10.1177/10600280211021417
Rosenthal, L. D., & Burchum, J. R. (2021). Lehne’s pharmacotherapeutics for advanced practice nurses and physician assistants (2nd ed.) St. Louis, MO: Elsevier.
Try it now!
How it works?
Follow these simple steps to get your paper done
Place your order
Fill in the order form and provide all details of your assignment.
Proceed with the payment
Choose the payment system that suits you most.
Receive the final file
Once your paper is ready, we will email it to you.
Our Services
Custom Writings Help is a Quality-Oriented Company in Online Writing as a result of hiring exceptional professionals to execute clients' tasks.
Essays
At Custom Writings Help,We understand the struggle of research paper writing, and that is why at Custom WritingS Help, we are all out to help you. We pride ourselves on having a team of clinical writers. The stringent and rigorous vetting process ensures that only the 'BEST' Writers are chosen for the job. We have highly qualified Ph.D. and MA writers working with us; we equally offer these experienced writers specific bonuses and incentives to make them deliver highly original, unique, and informative content at reasonably low prices.
Admissions
Thesis Writing Service
Worlwide, Many Masters Students are struggling with Thesis Completion. A thesis is likely to be the longest and most challenging piece of work a student has ever completed. However, unlike essays and other assignments, a student can pick a particular interest topic and work on their initiative. Fortunately, we are there for you. At Custom Writings Help, you are assured of an authentic, imaginative, informative, linguistically great, and advantageous thesis that adheres to all your needs. So, why continue considering different writers when you have discovered the best in the field?
Editing
Custom Papers
Not a single student can avoid writing custom papers. However, a total lack of experience, skills, and time makes it very hard to produce a superb writing piece. Therefore, if you are seeking professional help, turn to us. Our specialized and experienced writers compose a variety of model papers, including custom essays, college term papers, research papers, book reports, MBA essays, executive summaries, dissertations, Ph.D. theses, admission essays, and research proposals for college and university students at any level.
Coursework
Essay Writing
Most of the students disregard the critical principles of essay writing and compose papers below sensible guidelines. Therefore, with Custom Writings Help, one should not worry about his/her essay. Our Writers compose informative and engaging content on all complexities and topics. We write meaningful and smart essays while prioritizing all aspects that bring about a good grade, such as impeccable grammar, proper structure, zero-plagiarism, and conformance to guidelines.
Coursework
Coourse Work Writing
Don't let the seemingly never-ending onslaught of writing assignments get you down. If you are looking where to get course work assistance online, the writers at Custom Writings Help are here to assist you with all of your writing needs. We undertake to unique delivery of papers that meet the professor's requirements. The content is proofread, edited, and checked plagiarism before submission to customers. No matter how big or small your work is, we will deliver on time. Try US Now! !
Coursework
Dissertation Writing Service
High-Quality Dissertation Writing Services are rare. They require Ph.D. academicians – not easily found. However, are an exception. The years, time, and resources we have invested in the dissertation world has given us a competitive advantage over others. Choose to come to Custom Writings Help; You will find perfect Ph.D. consultants who have written hundreds of dissertations theses ready to help you. Let our dissertation-writing services help you craft your dissertation, for you are assured we will give you the results.